Viruses are constantly circulating and emerging, evolving rapidly to escape immune detection. In response, immune systems continuously adapt to recognize and neutralize these threats. This dynamic interplay shapes disease outcomes and presents a major challenge for predicting viral evolution and developing effective vaccines and therapies.
Through Mechanistic Understanding of Sequence Evolution (MUSE), we aim to create interpretable models that can anticipate viral evolution and guide the development of next-generation therapeutics and vaccines.
An iconic bacteriophage rendered as a vigilant sentinel, symbolizing precision in viral targeting and therapeutic design.
A tribute to Starry Night, reimagined with molecular textures—where patterns echo stochastic dynamics in evolution.
A playful take on affinity maturation: SARS‑CoV‑2 chisels an antibody form, reflecting coevolution and model-guided design.
We are actively recruiting PhD students and postdoctoral researchers.
wang.yiquan@ufl.edu
Veterinary Medicine Academic Building
1945 SW 16th Ave Suite V3-111, Gainesville, FL
https://github.com/Wang-Lab-UF